Vegan multinutrient supplementation significantly increases Omega-3 index and 25-OH-vitamin D status: a randomized, double-blind, placebo-controlled trial in healthy young vegans.
Prostaglandins Leukot Essent Fatty AcidsJul 12, 2026 (epub)
Tim Zerback, Christian Koeder, Stine Weder et al.
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In 30 seconds
This randomized, double-blind, placebo-controlled trial evaluated the effects of multinutrient supplementation on omega-3 index and vitamin D status in 72 healthy vegan adults aged 19-57. After 4 months, both intervention groups showed significant increases in omega-3 index and 25-hydroxyvitamin D compared to the control group (p < 0.001), with no significant difference between single and double doses.
Key findings
- Both intervention groups showed significant increases in omega-3 index and 25-hydroxyvitamin D (p < 0.001).
- The control group experienced a significant decline in omega-3 index and vitamin D levels.
- The double dose group had numerically greater increases in omega-3 index and vitamin D, but not statistically significant.
Why it matters
Improving omega-3 and vitamin D status in vegans may have important health implications, particularly given the potential roles of these nutrients in various physiological processes and disease prevention.