Factors influencing vaccine uptake during pregnancy: A systematic literature review.
Hum Vaccin ImmunotherJul 22, 2026 (epub)
Dasha Shamarina, Lina María Cortes Rueda, David Alderson et al.
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In 30 seconds
This systematic literature review analyzed 184 studies to identify factors influencing maternal immunization uptake during pregnancy. The review highlighted that barriers such as lack of knowledge and vaccine safety concerns significantly contribute to vaccine hesitancy. Conversely, proactive communication from healthcare professionals and trust in their recommendations were key enablers of vaccine acceptance.
Key findings
- Barriers to vaccine uptake included lack of knowledge and pre-existing anti-vaccination beliefs.
- Proactive communication from healthcare professionals significantly promoted vaccine acceptance.
- Trust in healthcare authorities was identified as a major enabler of maternal immunization.
- Vaccine hesitancy is a complex phenomenon influenced by both individual perceptions and social factors.
Why it matters
Understanding the factors that influence vaccine uptake during pregnancy is crucial for developing effective strategies to improve maternal immunization rates, ultimately protecting both mothers and newborns from serious infections.