Laparoscopic extended cholecystectomy with extended left hemi-hepatectomy (left lobe & S5), after interventional therapy and neoadjuvant chemotherapy for stage IIIb GBC.
Clive Delroy Ferguson, Hai-Jie Hu, Yan-Wen Jin et al.
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From the abstract
The benefits of the use of interventional therapy and neoadjuvant chemotherapy [1] to improve post-operative outcomes and potentially reduce the rate of recurrence during a laparoscopic extended cholecystectomy with extended left hemi-hepatectomy (left lobe & S5) for a T3N1M0 (Stage IIIb) Gallbladder Cancer (GBC).
Reported results
This minimally invasive extended cholecystectomy with extended left hemi-hepatectomy (LHH) was successfully completed in the duration of 260 minutes with estimated blood loss of 150ml. The frozen section sample of the cystic duct stump was found to be negative.
Authors' conclusions
The use of tri-modal therapy of HAIC and TACE with neoadjuvant SACT (Lin et al., 2024) [3] showed a positive effect on the tumor by downstaging the cancer, thereby reducing the size of the tumor and in turn reducing the risk of surgery by maintaining a healthy FLR. Furthermore, adequate liver resection of Liver segments 2,3,4 and 5 lead to a lower recurrence rate.