Effects of nutritional therapy on morphofunctional outcomes in critically ill patients: A systematic narrative synthesis.

Clin Nutr ESPENJul 23, 2026 (epub)

Carla Gabriela Fernandes da Silva, Aline Alves Soares, Sancha Helena de Lima Vale

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In 30 seconds

This systematic review examined the effects of nutritional therapy on morphofunctional outcomes in critically ill adult ICU patients. It included 29 studies and found that high-protein strategies had the most positive effects on muscle mass, while physical function showed limited responsiveness. The review highlights the need for integrated evaluations of muscle mass, strength, and function.

Key findings

  • High-protein strategies showed the greatest positive effects on muscle mass.
  • Muscle strength had a higher proportion of positive responses when linked to muscle mass.
  • Physical function demonstrated less responsiveness to nutritional interventions.
  • Only three studies evaluated muscle mass, strength, and function together.

Why it matters

Understanding the impact of nutritional therapy on morphofunctional outcomes is crucial for improving recovery and quality of life in critically ill patients. This knowledge can guide clinicians in optimizing nutritional strategies during and after ICU admission.

Source

Published in Clin Nutr ESPEN. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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