Adverse outcome in Cesarean scar pregnancy continuing into mid-to-late gestation: systematic review and meta-analysis.
Ultrasound Obstet GynecolJul 23, 2026 (epub)
Clinical ResearchObstetrics & Gynecology
S Zeng, Y Tian, J Qu et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the incidence and risk of placenta accreta spectrum (PAS) disorders and hysterectomy in women with Cesarean scar pregnancy (CSP) continuing into mid-to-late gestation. Among 432 cases, the pooled incidence of PAS was 0.90 and hysterectomy was 0.39. Type-III and exogenous CSPs were linked to higher risks compared to other subtypes.
Key findings
- Pooled incidence of placenta accreta spectrum (PAS) was 0.90 (95% CI, 0.81-0.96).
- Pooled incidence of hysterectomy was 0.39 (95% CI, 0.22-0.57).
- Type-III and exogenous CSPs had significantly higher odds of invasive PAS and hysterectomy.
- Pooled incidence of reaching term (≥ 37 weeks) was 0.19 (95% CI, 0.10-0.30).
Why it matters
Understanding the risks associated with different CSP subtypes is crucial for clinicians in order to provide appropriate counseling and management strategies for affected patients, particularly regarding the potential for severe complications.