Infertility treatment in women with epilepsy: A systematic review.

Epilepsy BehavJul 23, 2026 (epub)
Clinical ResearchObstetrics & GynecologyNeurology

Ola Alshaqi, Mathias Maisenbacher, Yazan Nofal et al.

✦ AI-curated · Sources linked

Condensed from the publisher's abstract. An xxcode editorial summary of this publication has not been generated yet.

From the abstract

The impact of assisted reproductive technologies (ART) on seizure control in women with epilepsy remains incompletely understood.

Reported results

A total of 1216 publications were identified, of which four studies met the inclusion criteria, including case reports, a case series, and a cohort study. These studies included 16 women aged 25-46 years undergoing infertility treatment, all but one of whom had epilepsy. Interventions involved in vitro fertilization (IVF), ovulation induction, and hormonal therapies.

Authors' conclusions

Available evidence suggests that ART is feasible in women with epilepsy, with most patients maintaining stable seizure control. Hormonal therapy may affect ASM pharmacokinetics and seizure threshold, thereby warranting close monitoring. Larger prospective studies are needed to better define ASM-specific effects and optimize care.

Source

PubMed · PMID 42492305

Published in Epilepsy Behav. The text above is extracted from the publisher's own abstract and has not been edited by xxcode. For clinical decisions, review the original publication.

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