Acute Kidney Injury After Intensive Blood Pressure Lowering Following Successful Endovascular Thrombectomy.
Jae Wook Jung, Hee Byung Koh, Young Dae Kim et al.
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In 30 seconds
This randomized controlled trial analyzed the impact of intensive blood pressure management on acute kidney injury (AKI) in 287 patients with acute ischemic stroke post-endovascular thrombectomy. The study found that AKI within 7 days occurred more frequently in the intensive management group (13.6%) compared to the conventional group (6.4%), with an adjusted odds ratio of 2.54.
Key findings
- AKI within 7 days was more frequent in the intensive group (13.6%) than in the conventional group (6.4%).
- Patients with AKI had significantly lower rates of functional independence (13.8% vs 49.0%).
- AKI was associated with higher stroke-related mortality at 3 months (37.9% vs 3.1%).
Why it matters
The findings highlight the potential risks associated with aggressive blood pressure management in stroke patients, particularly regarding kidney function and long-term outcomes. Understanding these risks is crucial for optimizing post-thrombectomy care.