Cervical cancer screening among transgender and gender diverse individuals: a systematic review and meta-analysis.
Amelia Srajer, John M Hutchinson, Amy Metcalfe et al.
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In 30 seconds
This systematic review and meta-analysis examined cervical cancer screening participation and Pap cytology results among transgender/gender diverse individuals compared to cisgender females. The analysis included 21 studies, revealing that transgender/gender diverse individuals had significantly lower odds of being up to date on cervical cancer screening (odds ratio 0.53) and more than 9-fold higher odds of un-satisfactory cytology (odds ratio 9.92).
Key findings
- Transgender/gender diverse individuals had lower odds of being up to date on cervical cancer screening (odds ratio 0.53).
- They had more than 9-fold higher odds of un-satisfactory Pap cytology (odds ratio 9.92).
- Abnormal cytology rates did not differ significantly between groups (odds ratio 0.75).
- Lower odds of abnormal cytology were noted in studies with mixed testosterone use (odds ratio 0.44).
Why it matters
These findings highlight significant disparities in cervical cancer screening among transgender and gender diverse individuals, emphasizing the need for tailored screening guidelines to enhance participation and outcomes in this population.