Antimicrobial photodynamic therapy improves wound quality and tissue repair in diabetic foot ulcers: A randomized double blind controlled clinical trial.
J Photochem Photobiol BJul 19, 2026 (epub)
Priscilla Farias Chagas, Thais Barbosa Dos Santos, Gesiane Dos Santos Trivino et al.
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In 30 seconds
This randomized controlled trial assessed the effects of antimicrobial photodynamic therapy (aPDT) on wound quality and tissue repair in patients with diabetic foot ulcers. The study found that the aPDT group showed significant reductions in Bates-Jensen Wound Assessment Tool scores from the third treatment session onward, with improvements sustained at a 30-day follow-up.
Key findings
- The aPDT group showed significant reductions in BWAT scores from the third treatment session onward.
- Improvements in wound quality were maintained at the 30-day follow-up.
- Significant enhancements in ischemic condition, epithelialization, and overall skin integrity were observed exclusively in the aPDT group.
- No treatment-related adverse events were reported during the study.
Why it matters
Improving wound quality and tissue repair in diabetic foot ulcers is crucial for enhancing patient quality of life and preventing complications. This study suggests that aPDT may be a beneficial adjunct to standard care.