Age Is an Effect Modifier of Thrombectomy Benefit in a Socioeconomically Vulnerable Stroke Population.
Fabricio O Lima, Francisco José de A Mont'Alverne, Letícia C Rebello et al.
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In 30 seconds
This multicenter, randomized controlled trial analyzed the impact of age on outcomes of endovascular treatment (EVT) for large vessel occlusion stroke in a socioeconomically vulnerable population in Brazil. Among 221 patients, increasing age was linked to lower odds of functional independence, with non-elderly patients showing significant benefit from EVT (OR: 4.08), while elderly and very elderly patients had diminished benefits (OR: 0.90 and OR: 0.36, respectively).
Key findings
- Increasing age was associated with lower odds of functional independence (OR: 0.97).
- Non-elderly patients derived substantial benefit from EVT (OR: 4.08).
- Elderly patients showed attenuated benefit from EVT (OR: 0.90).
- Very elderly patients had even lower odds of benefit from EVT (OR: 0.36).
Why it matters
Understanding how age modifies the effectiveness of EVT in diverse healthcare settings is crucial for optimizing treatment strategies for stroke patients, particularly in resource-limited environments.