BioGlue-induced inflammatory reaction mimicking oncologic recurrence in head and neck surgery: a case report.
Peter Nagy, Laurent Ganry, Michiya Nishino et al.
✦ AI-curated · Sources linked
Case in brief
A patient underwent cervical lymph node dissection where BioGlue was applied, leading to a mass-forming inflammatory reaction that resembled recurrent malignancy on imaging studies. Further evaluation through fine-needle aspiration and core needle biopsy confirmed a granulomatous foreign-body reaction, with no malignancy detected. The patient was managed with observation, and follow-up imaging showed stability at 12 months.
What made this case unusual
The inflammatory reaction caused by BioGlue mimicked oncologic recurrence, presenting a significant diagnostic challenge in postoperative imaging.
Diagnostic / clinical pearl
Clinicians should be aware that BioGlue can induce inflammatory reactions that may be mistaken for malignancy on imaging, necessitating careful evaluation.
Why it matters
This case underscores the importance of recognizing potential complications from surgical materials in postoperative oncologic surveillance, which can impact patient management.