Effects of time-restricted eating on markers of glucose metabolism and regulation in individuals with prediabetes or type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials.
Frida Viple, Sofie S Pedersen, Tue H Andersen et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the impact of time-restricted eating (TRE) on glucose metabolism in individuals with prediabetes or type 2 diabetes. Analyzing ten randomized controlled trials with 599 participants, the study found that TRE significantly reduced fasting blood glucose by 0.30 mmol/l (p<0.01) but had no overall effect on HbA1c levels. Subgroup analysis indicated improvements in HbA1c for prediabetes patients.
Key findings
- TRE reduced fasting blood glucose by 0.30 mmol/l (p<0.01) in the pooled analysis.
- In individuals with prediabetes, TRE improved HbA1c by 0.93 mmol/mol (p=0.02).
- TRE lowered body weight by 1.6 kg (p<0.001) in the pooled analysis.
- No overall effect of TRE on HbA1c was observed (p=0.06).
Why it matters
Understanding the effects of time-restricted eating on glucose regulation is crucial for managing prediabetes and type 2 diabetes. This evidence may inform dietary recommendations and lifestyle interventions aimed at improving metabolic health in these populations.