Clinical and Metabolic Effects of Preoperative Carbohydrate Loading Before Colorectal Surgery: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Henrique B Pivetta, Rodrigo O Massoud, Marcílio O Filho et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the effects of preoperative carbohydrate loading in 1387 patients undergoing colorectal surgery. Compared to traditional fasting, carbohydrate beverages did not significantly alter plasma insulin or blood glucose levels but were associated with a reduced length of hospital stay (LOS) by 1.71 days and earlier time to first defecation by 0.95 days.
Key findings
- No significant differences in plasma insulin levels at operating room admission or 24 h postoperatively.
- Blood glucose levels were similar at both operating room admission and 24 h postoperatively.
- Length of hospital stay was reduced by 1.71 days in the carbohydrate group.
- Time to first defecation was reduced by 0.95 days in the carbohydrate group.
Why it matters
Understanding the impact of preoperative carbohydrate loading can help clinicians optimize patient recovery after colorectal surgery, potentially leading to shorter hospital stays and improved gastrointestinal function without increasing complications.