Efficacy and safety of one anastomosis gastric bypass in long-term follow-up: a meta-analysis of studies with at least 10 years of follow-up.
J Gastrointest SurgJul 27, 2026 (epub)
Shahriar Azizi, Haval Sabir Faqismail, Mohammad Mehdi Zare et al.
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In 30 seconds
This meta-analysis evaluated the long-term outcomes of one anastomosis gastric bypass (OAGB) in 1729 patients with at least 10 years of follow-up. The study found a mean body mass index reduction of 15.41 kg/m² at 10 years and a total weight loss of 31.80%. OAGB showed favorable metabolic outcomes and acceptable safety profiles.
Key findings
- Mean body mass index reduction of 15.41 kg/m² at 10 years.
- Total weight loss of 31.80% at 10 years.
- Resolution rates for type 2 diabetes, hypertension, dyslipidemia, and obstructive sleep apnea were 72%, 66%, 67%, and 86%, respectively.
- Incidence of de novo gastroesophageal reflux disease was 6%.
Why it matters
Understanding the long-term efficacy and safety of OAGB is crucial for clinicians involved in weight loss surgery, as it informs patient selection and management strategies for obesity-related comorbidities.