Systematic Review, Meta-analysis and Meta-regression on the Prognostic Impact of Narrow Aortic Bifurcation on Outcomes of Endovascular Aneurysm Repair.
Mario D'Oria, Davide Mastrorilli, Antonino Maria Logiacco et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the outcomes of endovascular aortic repair (EVAR) in patients with narrow aortic bifurcation (NAB) compared to conventional aortic bifurcation (RAB). Analyzing data from approximately 2,300 patients across twelve studies, the results indicated no significant differences in primary limb patency, reintervention, or overall mortality, with pooled odds ratios of 0.96, 1.12, and 0.89, respectively.
Key findings
- No significant difference in primary limb patency between NAB and RAB with a pooled OR of 0.96.
- Reintervention rates were similar for NAB and RAB, with a pooled OR of 1.12.
- Overall mortality showed no significant difference, with a pooled OR of 0.89.
- Moderate heterogeneity was observed across all outcomes (I² = 25%-48%; P > .10).
Why it matters
Understanding the impact of aortic bifurcation morphology on EVAR outcomes is crucial for optimizing patient selection and procedural planning. This study suggests that NAB does not adversely affect key outcomes, potentially expanding the applicability of endovascular techniques.