Long-term follow-up, complications and outcomes of Meso-Rex bypass for extrahepatic portal vein obstruction (EHPVO): a systematic review.
Dig Liver DisJul 27, 2026 (epub)
Pietro Riva, Luca Pio, Angelo Zarfati et al.
✦ AI-curated · Sources linked
In 30 seconds
This systematic review evaluated long-term outcomes of Meso-Rex Bypass (MRB) in pediatric patients with extrahepatic portal vein obstruction (EHPVO). Analyzing 40 studies with 1403 MRB operations, the review found shunt patency in 87% of cases. The median follow-up was 30 months, revealing significant improvements in hematologic parameters and spleen size.
Key findings
- Shunt patency was achieved in 87% (1229/1403) of MRB operations.
- Recurrent gastrointestinal bleeding occurred in 13% (92/730) of patients.
- All studies evaluating portal pressures reported decreases, though mean postoperative values remained above 10 mmHg.
- Five patients (0.3%) died, with one death related to MRB.
Why it matters
Understanding the long-term outcomes of MRB in pediatric EHPVO is crucial for clinicians managing this condition, as it highlights the procedure's effectiveness in improving hematologic parameters and reducing complications.