Vulvar Crohn's-Case Series and Review of Treatment With Ustekinumab.
Emily M Conlin, Diane E Elas, Abigail A Bartolo-Costello et al.
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Case in brief
This case series presents three patients with cutaneous vulvar Crohn's disease (VCD), a rare and challenging condition. Each patient was treated with different biologic agents. Ustekinumab successfully achieved remission in the first patient, while risankizumab controlled symptoms in the third. The series emphasizes the need for a tailored treatment approach based on individual disease characteristics and treatment history.
Diagnostic / clinical pearl
Clinicians should consider biologic agents like ustekinumab and risankizumab for managing refractory vulvar Crohn's disease, especially after TNF-alpha inhibitors fail.
Why it matters
This case series underscores the importance of personalized treatment strategies in managing complex cases of cutaneous vulvar Crohn's disease.