Graves' Orbitopathy and Anophthalmia.
Marta Pérez-López, Petros Perros
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Case in brief
This report details four cases of Graves' orbitopathy (GO) in patients with anophthalmia in one eye. All cases exhibited clinical and radiological signs of GO in the anophthalmic eye, with two patients experiencing optic nerve compression. Radiological assessments revealed symmetrical involvement of extraocular muscles in both orbits, highlighting the unique presentation of GO in this context.
Diagnostic / clinical pearl
Clinicians should be aware that Graves' orbitopathy can occur in patients with anophthalmia, necessitating careful evaluation and management to preserve any remaining visual function.
Why it matters
Understanding the relationship between anophthalmia and Graves' orbitopathy may offer insights into the disease's pathogenesis and improve management strategies for affected patients.