Does the prophylactic use of compression garments reduce the risk of lower limb lymphedema after pelvic and/or inguinal lymphadenectomy for gynecological cancer? A systematic review.
Stefano Gentileschi, Giorgia Garganese, Simona Maria Fragomeni et al.
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In 30 seconds
This systematic review evaluated the effectiveness of prophylactic compression garments in reducing lower-limb lymphedema after pelvic and/or inguinal lymphadenectomy in women with gynecological cancer. Among six randomized controlled trials, one study reported a significant reduction in lymphedema incidence (3.4% vs 38.7%) with the use of class II stockings for 12 months, alongside education and physical activity.
Key findings
- One trial showed a reduction in lymphedema incidence from 38.7% to 3.4% with class II stockings.
- Small trials using class I to II stockings did not show significant lymphedema reduction.
- Evidence is limited by the heterogeneity of trials and multimodal interventions.
Why it matters
Understanding the role of prophylactic compression garments can help clinicians make informed decisions about lymphedema prevention strategies in patients undergoing lymphadenectomy for gynecological cancers, potentially improving patient outcomes.
What to keep in mind
The review is limited by small, heterogeneous trials and the absence of a meta-analysis.