Association between sleep disorders during pregnancy and hypertensive disorders of pregnancy: A systematic review and meta-analysis of cohort studies.
Si-Jie Guo, Jia-Shuang Xu, Jie Cai et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the association between sleep disorders during pregnancy and hypertensive disorders in 9,460,018 women across 19 cohort studies. The analysis found significant associations, with gestational hypertension (OR = 1.50), preeclampsia (OR = 1.83), and hypertensive disorders of pregnancy (OR = 1.56) linked to sleep disorders, particularly obstructive sleep apnea, which had the strongest associations.
Key findings
- Sleep disorders during pregnancy are associated with a 50% increased risk of gestational hypertension (OR = 1.50).
- Preeclampsia risk is elevated by 83% in pregnant women with sleep disorders (OR = 1.83).
- Obstructive sleep apnea shows a strong association with hypertensive outcomes, with an OR of 2.13 for preeclampsia.
- Mid-pregnancy sleep-disordered breathing is linked to significantly increased risks of hypertensive disorders.
Why it matters
Understanding the link between sleep disorders and hypertensive conditions during pregnancy is crucial for clinicians. Identifying and managing sleep issues may help mitigate risks for adverse maternal outcomes, improving overall pregnancy health.