Thrombotic Microangiopathy After Kidney Transplantation Associated With Rifampicin: A Case Report.
Agatha Prado de Lima, Diogo Buarque Cordeiro Cabral, Alexandre de Holanda Cavalcanti Pinto et al.
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Case in brief
A patient developed thrombotic microangiopathy (TMA) following kidney transplantation, which was linked to the use of rifampicin. The diagnosis was made through careful exclusion of other causes and a high index of suspicion. Upon identifying rifampicin as a potential trigger, the drug was promptly withdrawn, leading to an improvement in the patient's condition and graft function.
Diagnostic / clinical pearl
Clinicians should maintain a high index of suspicion for thrombotic microangiopathy in kidney transplant patients, especially when rifampicin is part of the medication regimen.
Why it matters
Recognizing rifampicin as a potential trigger for TMA can significantly influence patient management and improve outcomes following kidney transplantation.