A case of bone marrow-liver-spleen type diffuse large B-cell lymphoma: importance of rapid diagnosis and therapeutic intervention.
Hitomi Eda, Kaoru Furihata, Fumiya Ogasawara
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Case in brief
A 73-year-old woman presented with multiorgan failure and disseminated intravascular coagulation, raising concerns for secondary hemophagocytic lymphohistiocytosis. Diagnosis of bone marrow-liver-spleen type diffuse large B-cell lymphoma was confirmed through bone marrow smear examination. Intensive chemotherapy with R-CHOP was initiated promptly, leading to rapid clinical improvement and prolonged survival.
Diagnostic / clinical pearl
Timely diagnosis and initiation of lymphoma-directed treatment based on clinical and hematologic findings are crucial in managing bone marrow-liver-spleen type diffuse large B-cell lymphoma.