FDG PET/CT in a Case of α-Fetoprotein-Producing Urothelial Carcinoma With Hepatoid Differentiation of the Renal Pelvis.
Xiaojun Man, Changming Dong, Aisheng Dong et al.
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Case in brief
A patient presented with a tumor in the left renal pelvis that produced elevated serum alpha-fetoprotein levels (1035 ng/mL). FDG PET/CT imaging revealed intense activity in the tumor, which was found to invade the renal parenchyma. The case highlights the significance of recognizing this type of urothelial carcinoma in the context of elevated alpha-fetoprotein.
Diagnostic / clinical pearl
Clinicians should consider alpha-fetoprotein-producing urothelial carcinoma with hepatoid differentiation in the differential diagnosis of FDG-avid urinary tract tumors, especially in patients with elevated serum alpha-fetoprotein levels.