Evaluating the association between potentially morally injurious events (PMIEs) and types of psychological distress. A systematic review.

Eur J PsychotraumatolJul 31, 2026 (epub)
Clinical ResearchPsychiatryOpen access

Andreana Farrell Kakouris, Dominic Murphy, Neil Greenberg et al.

✦ AI-curated · Sources linked

In 30 seconds

This systematic review analyzed 15 quantitative studies involving approximately 21,700 participants to explore the relationship between different subtypes of potentially morally injurious events (PMIEs) and psychological distress. The findings indicated that betrayal-type PMIEs were consistently associated with PTSD, depression, and anxiety, while commission-type events were linked to various outcomes, including suicidality. Omission-type events showed less consistent associations.

Key findings

  • Betrayal-type PMIEs were frequently associated with PTSD, depression, and anxiety across studies.
  • Commission-type PMIEs were linked to PTSD, depression, and suicidality, though findings varied.
  • Omission-type PMIEs demonstrated more variable associations with psychological distress.
  • Different PMIE subtypes may carry distinct patterns of risk for psychological outcomes.

Why it matters

Understanding the specific psychological impacts of different PMIE subtypes can enhance assessment and treatment strategies for individuals experiencing moral injury, potentially leading to more tailored interventions and improved mental health outcomes.

Source

PubMed · PMID 42535794Free full text on PubMed Central

Published in Eur J Psychotraumatol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

ShareTelegramLinkedIn

AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

More in Psychiatry

Clinical ResearchHematology

Ponatinib-Blinatumomab or Imatinib-Chemotherapy for Adult Ph-Positive ALL.

This multicenter, phase 3 randomized trial compared frontline ponatinib plus blinatumomab with imatinib plus chemotherapy in adults with Philadelphia-positive acute lymphoblastic leukemia.

N Engl J MedOct 15, 2026Read summary
Clinical ResearchHematology

Efficacy and safety of mitapivat in patients with sickle cell disease (RISE UP): a phase 3, double-blind, global, randomised, placebo-controlled trial.

RISE UP was a phase 3, double-blind, global, randomised, placebo-controlled trial conducted at 69 sites in 15 countries. It evaluated twice-daily mitapivat in patients older than 16 years with sickle cell disease…

LancetOct 24, 2026Read summary
Clinical ResearchRheumatology

Ianalumab for the Treatment of Patients with Sjögren's Disease.

Two 52-week, double-blind, randomized, placebo-controlled phase III trials evaluated monthly or less frequent ianalumab in patients with active Sjögren's disease.

N Engl J MedOct 22, 2026Read summary

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text
Create my personalized digestSee plans

Prefer listening? Personalized audio digests are available with Pro.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.