Mental simulation practices in stroke rehabilitation reorganize brain connectivity: a systematic review.

J Stroke Cerebrovasc DisJul 31, 2026 (epub)
Clinical ResearchPhysical Medicine & RehabilitationNeurology

A Demeco, N Marotta, M P Lentini et al.

✦ AI-curated · Sources linked

In 30 seconds

This systematic review evaluated the effects of Mental Simulation Practices (MSP) on brain connectivity in stroke patients. Analyzing 8 randomized controlled trials with 249 participants, the review found that MSPs, particularly Motor Imagery, significantly improved upper limb motor function and reorganized brain networks, enhancing connectivity in sensorimotor regions compared to conventional rehabilitation.

Key findings

  • MSPs were associated with upper limb motor improvement compared to conventional rehabilitation.
  • Significant reorganization of brain networks was observed, enhancing connectivity in sensorimotor regions.
  • Normalization of maladaptive activation patterns and stronger interactions between motor and cognitive networks were reported.

Why it matters

Understanding the impact of MSPs on brain connectivity can inform rehabilitation strategies for stroke patients, potentially leading to improved motor recovery and functional outcomes. This knowledge may enhance the effectiveness of existing rehabilitation programs.

Source

PubMed · PMID 42537726

Published in J Stroke Cerebrovasc Dis. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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