More Prominent 18 F-FDG Uptake Than 68 Ga-FAPI-04 in Nongestational Choriocarcinoma.

Clin Nucl MedJul 23, 2026 (epub)
Case ReportOncology (Medical)Nuclear MedicineRadiology (Diagnostic)

Ya Liu, Ke Xiang, Miao Liu et al.

✦ AI-curated · Sources linked

Case in brief

A 56-year-old man was found to have nongestational choriocarcinoma of unknown primary with multiple metastases. On PET/CT, the lesions showed intense 18F-FDG uptake but limited accumulation of 68Ga-FAPI-04. The report describes this discordant tracer pattern in a rare male presentation of primary choriocarcinoma.

What made this case unusual

The metastatic lesions were markedly more conspicuous on 18F-FDG PET/CT than on 68Ga-FAPI-04 PET/CT, an unexpected imaging contrast in this case.

Diagnostic / clinical pearl

In this reported case, limited 68Ga-FAPI-04 accumulation did not correspond to low 18F-FDG uptake; the two tracers showed substantially different lesion uptake.

Source

PubMed · PMID 42545162

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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