Primary Osteosarcoma of the First Metatarsal With Multiple Metastases on 18F-FDG PET/CT.

Clin Nucl MedJul 22, 2026 (epub)

Guoxing Zhao, Peng Xie, Xin Liu et al.

✦ AI-curated · Sources linked

Case in brief

A patient presented with primary osteosarcoma located in the first metatarsal, an uncommon site for this type of tumor. Imaging with 18F-FDG PET/CT revealed multiple metastases, which were later confirmed through histopathological examination. The case highlights the diagnostic utility of PET/CT in identifying metastatic disease in atypical presentations of osteosarcoma.

What made this case unusual

The occurrence of primary osteosarcoma in the first metatarsal is rare, making this case noteworthy for its atypical location.

Diagnostic / clinical pearl

Clinicians should consider the possibility of osteosarcoma in unusual locations, such as the metatarsals, especially when evaluating bone lesions.

Why it matters

This case underscores the importance of advanced imaging techniques like 18F-FDG PET/CT in detecting metastases in atypical presentations of bone tumors.

Source

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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