Complete Pachydermoperiostosis With Acromegaloid Phenotype: Characteristic 99m Tc-Methylene Diphosphonate (MDP) Skeletal Scintigraphy in a Rare Clinical Mimic of Acromegaly.

From the abstract

Pachydermoperiostosis (Touraine-Solente-Gole syndrome) is a rare disorder that can mimic acromegaly and should be considered a differential in patients with acromegaloid features. A 21-year-old man with acral enlargement, coarse facial features, joint pain, and hyperhidrosis, initially evaluated for acromegaly but eventually diagnosed as familial complete pachydermoperiostosis.