Cognitive behavioural therapy-based interventions on stress outcomes in pregnant women: A systematic review and meta-analysis.

Int J Nurs StudJul 22, 2026 (epub)

Yu Shi, Ying Lau, Sin Lun Chan et al.

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In 30 seconds

This systematic review and meta-analysis evaluated the effectiveness of cognitive behavioural therapy (CBT) interventions on stress outcomes in 6966 pregnant women across 20 randomized controlled trials. The results indicated significant reductions in pregnancy-specific stress symptoms (Hedges' g = -0.84) and generic stress symptoms (g = -0.64) post-intervention, although no significant effect on cortisol levels was observed.

Key findings

  • CBT interventions significantly reduced pregnancy-specific stress symptoms with Hedges' g = -0.84.
  • Generic stress symptoms were reduced with a Hedges' g = -0.64.
  • No significant effect on cortisol levels was found (g = -0.99, p = .12).
  • Younger age and lower attrition rates improved intervention effectiveness.

Why it matters

Given the prevalence of stress during pregnancy, effective interventions like CBT can enhance antenatal care, potentially improving maternal and fetal outcomes. Understanding the factors influencing intervention effectiveness can guide future practices.

What to keep in mind

The overall certainty of the evidence was rated as very low or low, and substantial heterogeneity was noted among studies.

Source

Published in Int J Nurs Stud. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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