Effectiveness of transcranial direct current stimulation with and without positive mood induction on worry and transdiagnostic cognitive-emotional processes: A randomized controlled trial.

Physiol BehavAug 4, 2026 (epub)
Clinical ResearchPsychiatry

Fateme Shahsavari, Farzad Nasiri, Mehdi Zemestani

✦ AI-curated · Sources linked

In 30 seconds

This randomized controlled trial examined the effects of transcranial direct current stimulation (tDCS) with and without positive mood induction on worry and cognitive-emotional processes in 45 individuals with high worry levels. Results indicated that both active interventions significantly improved outcomes such as attentional bias and working memory compared to a sham control, with the combined intervention yielding greater benefits, particularly in working memory and emotion regulation.

Key findings

  • Both tDCS groups showed significant improvements in attentional bias and worry compared to controls (p < 0.05).
  • The combined tDCS and positive mood induction group had greater gains in working memory and problem solving (p < 0.05).
  • Reductions in attentional bias and worry were significantly greater in the combined intervention group (p < 0.001).
  • All effects were sustained at one-month follow-up (p < 0.05).

Why it matters

The study highlights the potential of tDCS, especially when combined with positive mood induction, to effectively reduce worry and enhance cognitive-emotional functioning in individuals with high levels of worry, suggesting new avenues for therapeutic interventions.

Source

Published in Physiol Behav. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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