A two-center randomized clinical superiority trial of single-anastomosis sleeve ileal bypass versus sleeve gastrectomy for severe obesity: SASSY study protocol.
Scand J SurgAug 5, 2026 (epub)
Helene M Haug, Rolf E Hagen, Jon A Kristinsson et al.
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In 30 seconds
The SASSY study is a two-center randomized clinical trial comparing single-anastomosis sleeve ileal bypass to sleeve gastrectomy in patients with class II and III obesity. The primary endpoint is the change in body mass index from baseline to 2 years post-surgery. This trial aims to provide robust data on the efficacy and safety of these surgical options.
Key findings
- Primary endpoint: change in body mass index from baseline to 2 years post-surgery.
- Secondary endpoints include weight loss outcomes, prevalence of gastroesophageal reflux disease, and quality of life.
- Evaluations will occur at 2 and 5 years after surgery.
Why it matters
Understanding the comparative effectiveness and safety of single-anastomosis sleeve ileal bypass versus sleeve gastrectomy is crucial for optimizing treatment strategies in patients with severe obesity and related comorbidities.