Secondary Ameloblastic Carcinoma With Craniofacial and Skull Base Invasion: En Bloc Resection and Dural Reconstruction.
Federico Sacasa, María Eugenia Lara, Melina Quezada et al.
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Case in brief
A 27-year-old male with a 13-year history of recurrent mandibular ameloblastoma presented with extensive craniofacial progression and regional lymph node metastases. He underwent radical en bloc craniofacial resection and modified radical neck dissection, with dural excision for margin control. Reconstruction involved multilayer vascularized pericranial-galeal techniques. After 42 months, the patient remains disease-free with stable craniofacial contour.
Diagnostic / clinical pearl
In cases of secondary ameloblastic carcinoma with craniofacial involvement, comprehensive surgical resection combined with meticulous reconstructive techniques is crucial for achieving favorable outcomes.
Why it matters
This case highlights the importance of integrating oncologic and reconstructive strategies in complex craniofacial tumors to ensure both disease control and functional preservation.