Management considerations of ameloblastic carcinoma in soft-tissue: case report and literature review.

Oral Surg Oral Med Oral Pathol Oral RadiolJul 1, 2026 (epub)
Case ReportOncology (Medical)

Padmaraj Hegde, Kritharth Sujith, Lida Mary Nidhin Philip

✦ AI-curated · Sources linked

Case in brief

A 36-year-old woman with a history of mandibular ameloblastoma underwent segmental mandibulectomy and reconstruction. Three years later, she presented with a submental swelling, which was initially diagnosed as recurrent follicular ameloblastoma. However, further histopathological analysis post-surgery revealed ameloblastic carcinoma. The patient received complete excision and neck dissection, and is under close surveillance for potential adjuvant therapy.

Diagnostic / clinical pearl

Clinicians should be aware that ameloblastic carcinoma can arise from previously treated ameloblastoma, presenting as soft-tissue recurrence and complicating management.

Why it matters

This case highlights the importance of thorough histopathological evaluation in cases of recurrent ameloblastoma, as malignant transformation can occur, necessitating a comprehensive treatment approach.

Source

PubMed · PMID 42562755

Published in Oral Surg Oral Med Oral Pathol Oral Radiol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

ShareTelegramLinkedIn

AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

More in Oncology (Medical)

Clinical ResearchOncology (Medical)

Zamtocabtagene autoleucel, a tandem CD20-CD19-directed CAR T-cell therapy, for second line treatment of large B-cell lymphoma in patients ineligible for transplantation (DALY 2-EU): primary analysis of an open-label, multicentre, randomised phase 2 study.

DALY 2-EU was an open-label, multicentre, randomised phase 2 trial comparing tandem CD20-CD19-directed zamtocabtagene autoleucel (zamto-cel) with R-GemOx in adults with second-line relapsed or refractory large B-cell…

Lancet OncolOct 27, 2026Read summary
Clinical ResearchOncology (Medical)

Neoadjuvant short-course radiotherapy followed by camrelizumab and chemotherapy versus standard of care for locally advanced rectal cancer (UNION): a prespecified interim analysis of a multicentre, open-label, randomised, phase 3 trial.

UNION was a multicentre, open-label, randomised phase 3 trial at nine hospitals in China comparing neoadjuvant short-course radiotherapy followed by camrelizumab plus CAPOX with long-course chemoradiotherapy followed by…

Lancet OncolOct 25, 2026Read summary
Clinical ResearchHematology

Efficacy and safety of mitapivat in patients with sickle cell disease (RISE UP): a phase 3, double-blind, global, randomised, placebo-controlled trial.

RISE UP was a phase 3, double-blind, global, randomised, placebo-controlled trial conducted at 69 sites in 15 countries. It evaluated twice-daily mitapivat in patients older than 16 years with sickle cell disease…

LancetOct 24, 2026Read summary

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text
Create my personalized digestSee plans

Prefer listening? Personalized audio digests are available with Pro.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.