Comparison of Iodinated Contrast Doses Based on Total Body Weight and Lean Body Weight in Pediatric Patients: Impact on Image Quality and Contrast Exposure.
Radiography (Lond)Aug 7, 2026 (epub)
L A O da Silva, F D C B Braga, M R R Cardoso et al.
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In 30 seconds
This randomized controlled trial evaluated iodinated contrast dosing in 66 pediatric patients (ages 0-16) undergoing abdominal CT, comparing lean body weight (LBW) and total body weight (TBW) dosing protocols. The LBW group received a median contrast volume of 27 mL, lower than the TBW group's 34.5 mL and the control group's 40 mL, without compromising hepatic enhancement quality.
Key findings
- The LBW group received a median contrast volume of 27 mL compared to 34.5 mL in the TBW group.
- The control group received a median contrast volume of 40 mL.
- Hepatic enhancement in the LBW group was comparable to the control group at 552 ± 139 HU.
Why it matters
Optimizing iodinated contrast dosing in pediatric patients is crucial to minimize exposure risks while maintaining image quality. This study suggests that LBW-based dosing may enhance individualized care in pediatric imaging.