Patient and public involvement in the co-design of a multicenter randomized controlled trial on prehabilitation: results from the PREHAB-PEER conceptual phase.
Eur J Surg OncolJul 28, 2026 (epub)
Magdalena Holze, Solveig Tenckhoff, Eva Kalkum et al.
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In 30 seconds
This study focused on the co-design of a multicenter randomized controlled trial (RCT) for prehabilitation in colorectal cancer (CRC) patients. Involving patients and stakeholders, the research aimed to create a patient-centered trial design addressing perioperative risks. The primary endpoint selected was Quality of Recovery, emphasizing the importance of patient input in trial development.
Key findings
- A patient-centered study design was developed for the PREHAB-PEER RCT over 12 months.
- The target population includes CRC patients with increased perioperative risk based on age, frailty, and nutrition status.
- Quality of Recovery was chosen as the primary endpoint for the trial.
Why it matters
Incorporating patient and stakeholder perspectives in trial design can enhance the relevance and feasibility of clinical research, ultimately leading to improved patient outcomes and adherence in complex interventions like prehabilitation.