Therapeutic targeting of folate receptor alpha (FRα) by antibody-polymer-drug conjugate in testicular germ cell tumors.

Biomed PharmacotherAug 8, 2026 (epub)
Case ReportOncology (Medical)

Lucia Kučerová, Robert Pola, Marcela Filipová et al.

✦ AI-curated · Sources linked

Condensed from the publisher's abstract. An xxcode editorial summary of this publication has not been generated yet.

From the abstract

Antibody-drug conjugates (ADCs) are an effective treatment for recurrent/refractory testicular germ cell tumors (rrTGCTs). In this exploratory study, we report disease stabilization achieved with the ADC Mirvetuximab soravtansine (MIRV) in a heavily pretreated patient with rrTGCT and compare this ADC with a novel antibody-polymer-drug conjugate (APDC) targeting folate receptor…

Source

PubMed · PMID 42570634

Published in Biomed Pharmacother. The text above is extracted from the publisher's own abstract and has not been edited by xxcode. For clinical decisions, review the original publication.

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