Aminolevulinic acid photodynamic therapy for extensive genital extramammary Paget disease in older patients: A retrospective clinical case series.

Photodiagnosis Photodyn TherAug 8, 2026 (epub)
Case ReportDermatologyGeriatrics

Xu Ji, Li Ma, Yu Xin Ding et al.

✦ AI-curated · Sources linked

Case in brief

Three older patients with extensive extramammary Paget disease (EMPD) affecting sensitive genital areas were treated with aminolevulinic acid photodynamic therapy (ALA-PDT) after declining surgery. Following treatment, erosive areas re-epithelialized, and nodular lesions significantly reduced. Patients experienced rapid relief from pruritus and local pain, with no signs of regrowth during a 12-month follow-up.

Diagnostic / clinical pearl

ALA-PDT can provide effective symptom relief and clinical control in older patients with extensive EMPD who are unsuitable for surgery.

Source

PubMed · PMID 42570749

Published in Photodiagnosis Photodyn Ther. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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