Metastatic Gastrointestinal Neuroectodermal Tumor Mimicking a Benign Hepatic Hemangioma on MRI: Role of 18 F-FDG PET/CT.

Clin Nucl MedAug 3, 2026 (epub)
Case ReportOncology (Medical)Radiology (Diagnostic)

En Ting Lin, Hao-Wei Chen, Chin-Ho Tsao et al.

✦ AI-curated · Sources linked

Case in brief

A 27-year-old man with proximal jejunal gastrointestinal neuroectodermal tumor (GNET) underwent segmental resection and adjuvant chemotherapy. During surveillance, MRI identified a 0.8-cm caudate-lobe lesion interpreted as a hemangioma. Eight months later, 18F-FDG PET/CT showed intense focal uptake (early/delayed SUVmax: 7.54/9.13), while repeat MRI showed enlargement to 1.4 cm, favoring hepatic metastasis. The lesion was treated with radiofrequency ablation, and follow-up imaging showed no residual or recurrent disease.

What made this case unusual

The hepatic metastasis initially resembled a benign hemangioma on MRI; interval growth and intense 18F-FDG uptake shifted the interpretation toward metastasis.

Diagnostic / clinical pearl

In a patient with GNET, a liver lesion interpreted as a hemangioma on MRI may warrant reassessment when it enlarges; 18F-FDG PET/CT can provide additional evidence favoring metastasis.

Source

PubMed · PMID 42573162

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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