Oliceridine used for patient-controlled analgesia on postoperative quality of recovery in patients undergoing laparoscopic gynecological tumour resection: a randomized clinical trial.
Chunyan Li, Xinna Luo, Yanli Du et al.
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In 30 seconds
This randomized clinical trial evaluated the effects of oliceridine-based patient-controlled intravenous analgesia (PCIA) on postoperative recovery quality in 94 female patients undergoing laparoscopic gynecological tumor resection. The study found that the oliceridine group had a significantly higher Quality of Recovery-40 (QoR-40) score on postoperative day 1 (182.9 ± 3.1 vs 177.5 ± 3.9, p < 0.001) compared to the sufentanil group.
Key findings
- Oliceridine group had a QoR-40 score of 182.9 ± 3.1 on postoperative day 1.
- Oliceridine showed better QoR-40 scores within 3 days post-operation compared to sufentanil.
- Median FRAIL score was lower in the oliceridine group on postoperative day 2 (p = 0.018).
- No significant differences in NRS pain scores or HADS-A scores between groups.
Why it matters
Improving postoperative recovery quality is crucial for enhancing patient outcomes. This study suggests that oliceridine may offer a beneficial alternative to traditional opioids, potentially leading to better recovery experiences for patients undergoing gynecological surgeries.