EEG-Guided Sevoflurane Anesthesia and Emergence Delirium in Children: A Randomized Controlled Trial.
Paediatr AnaesthAug 12, 2026 (epub)
Ozlem Kocaturk, Sultan Keles
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In 30 seconds
This randomized controlled trial evaluated EEG-guided anesthesia using SedLine in 100 children aged 4-10 undergoing dental procedures. The study found that EEG-guided anesthesia significantly reduced the incidence of emergence delirium (ED) compared to standard MAC-guided anesthesia, with 17% vs. 43% incidence upon arrival in the recovery room.
Key findings
- Median PAEDS scores were significantly lower in the EEG-S group (4 vs. 8) during the first 120 minutes postoperatively.
- The incidence of ED was 17% in the EEG-S group compared to 43% in the standard group upon arrival in the recovery room.
- Mean end-tidal sevoflurane concentration was lower in the EEG-S group (1.88 ± 0.25 vs. 1.98 ± 0.20).
- Postoperative FLACC pain scores were lower in the EEG-S group, potentially confounding ED outcomes.
Why it matters
The findings suggest that EEG-guided anesthesia may enhance recovery by reducing emergence delirium in pediatric patients, which is crucial for improving postoperative outcomes and patient comfort.