Comparing efficacy in glycaemic control and pregnancy outcomes between continuous glucose monitoring and self-monitoring of blood glucose in pregnancies complicated by gestational diabetes mellitus: a systematic review and meta-analysis.
Shirlyn Yang, Emelia Tze-Ting Boon, Qian Yang et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the efficacy of continuous glucose monitoring (CGM) versus self-monitoring of blood glucose (SMBG) in 5,650 pregnant women with gestational diabetes mellitus (GDM). The study found that CGM significantly lowered mean blood glucose levels by -0.24 mmol/L (95% CI: -0.41, -0.06) compared to SMBG, while also reducing adverse maternal and neonatal outcomes.
Key findings
- CGM significantly reduced mean blood glucose by -0.24 mmol/L compared to SMBG.
- CGM was associated with a 21% increase in medication use.
- Adverse maternal and neonatal outcomes were reduced by 8-35% with CGM.
- CGM lowered the coefficient-of-variation by -0.78% compared to SMBG.
Why it matters
Improving glycaemic control in pregnancies complicated by GDM is crucial for reducing risks of adverse outcomes for both mothers and infants. This evidence supports the potential benefits of CGM in clinical practice.