Comparison of the Effects of Spinal Versus General Anesthesia on the Perioperative Intraocular Pressure: A prospective, randomized clinical trial .
Saudi Med JAug 6, 2026 (epub)
Muzaffer Gencer, Mehmet Yalvaç
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In 30 seconds
This randomized controlled trial evaluated the effects of spinal versus general anesthesia on intraocular pressure (IOP) in 60 adults undergoing lumbar spine and lower extremity orthopedic surgeries. The study found that while IOP decreased significantly after anesthesia induction, the increase in IOP during the intraoperative period was greater in the general anesthesia group compared to the spinal anesthesia group.
Key findings
- The most significant decrease in IOP was recorded at T2: SA 12.37 mmHg vs GA 12.24 mmHg, p < 0.001.
- IOP after intubation was significantly higher in the GA group: GA 19.82 mmHg vs SA 12.86 mmHg, p < 0.05.
- IOP at T4 and T5 was significantly higher than baseline in both groups, with GA showing a greater increase.
Why it matters
Understanding the impact of different anesthesia techniques on IOP is crucial for clinicians managing patients at risk for ocular complications during surgery, particularly in those undergoing procedures involving the spine and lower extremities.