68 Ga-FAPI-04 PET/CT Findings in Primary Hyperoxaluria Type 1.
Guorong Jia, Jinming Tian, Chao Cheng et al.
✦ AI-curated · Sources linked
Case in brief
A patient with primary hyperoxaluria type 1 presented with systemic oxalate deposition leading to end-stage renal disease. 68 Ga-FAPI-04 PET/CT imaging revealed significant FAPI uptake in various bones and joints, indicating an active fibroblastic repair process associated with oxalate crystal deposition. The case highlights the imaging characteristics of this rare condition.
What made this case unusual
The notable FAPI uptake in multiple bones and joints is an atypical imaging finding that reflects the underlying fibroblastic repair process due to oxalate crystal deposition.
Diagnostic / clinical pearl
Clinicians should consider the unique imaging patterns of 68 Ga-FAPI-04 PET/CT in cases of primary hyperoxaluria type 1, as they may indicate active disease processes.
Why it matters
Understanding the imaging manifestations of primary hyperoxaluria type 1 can aid in the diagnosis and management of this rare genetic disorder.