Optimal aerobic exercise dose for improving metabolic health and functional outcomes in frail older adults: A systematic review and dose-response meta-analysis.

Clin NutrAug 1, 2026 (epub)

Huanhuan Luo, Zitian Zheng, Mingyao Sun et al.

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In 30 seconds

This systematic review and dose-response meta-analysis evaluated the effects of aerobic exercise on frailty and health outcomes in adults aged 60 and older. The analysis included 44 studies with 4011 participants, revealing that aerobic exercise significantly improved frailty status (Hedges' g = 0.34), depressive symptoms, muscle strength, cognitive function, quality of life, and lower-limb function compared to usual care.

Key findings

  • Aerobic exercise improved frailty status with a Hedges' g of 0.34.
  • Cognitive function showed a significant improvement with a Hedges' g of 0.67.
  • Quality of life improved significantly, with a Hedges' g of 0.57.
  • No single type of aerobic exercise was found to be superior across modalities.

Why it matters

Understanding the impact of aerobic exercise on frailty and related health outcomes is crucial for developing effective interventions in older adults. This evidence can guide clinicians in recommending exercise as a strategy to enhance overall health and functional status in frail populations.

Source

Published in Clin Nutr. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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