Fluorescence patterns and longitudinal changes of oral potentially malignant disorders (OPMDs) lesions using biofluorescence imaging: case reports.
Eun Po, Areum Kim, Eun-Song Lee et al.
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Case in brief
Two patients with oral potentially malignant disorders (OPMDs) were monitored using biofluorescence imaging alongside white-light imaging. Both cases exhibited histopathological findings of moderate to severe epithelial dysplasia, hyperkeratosis, and acanthosis. Over time, fluorescence patterns revealed distinct changes in lesion margins, with one case showing fluorescence loss and the other displaying areas of red fluorescence, enhancing visualization of lesion boundaries compared to white-light images.
Diagnostic / clinical pearl
Biofluorescence imaging can provide valuable insights into the margins and changes of OPMD lesions, potentially improving non-invasive monitoring and clinical decision-making.