Negative autofluorescence in benign exophytic lesions highly suspicious for malignancy: importance of the tool as a rapid screening method for lesions requiring biopsy.
Photodiagnosis Photodyn TherAug 20, 2026 (epub)
Case ReportOtolaryngology (ENT)
Cinzia Casu, Germano Orrù
✦ AI-curated · Sources linked
Case in brief
Two patients presented with irregular exophytic lesions in the oral cavity that were highly suspicious for malignancy. Autofluorescence imaging revealed a loss of fluorescence in these lesions, indicating a benign nature despite their concerning appearance. This diagnostic tool effectively differentiated between benign reactive lesions and malignant tumors, guiding the decision for biopsy.
Diagnostic / clinical pearl
Autofluorescence imaging can be a valuable rapid screening method to differentiate benign lesions from malignancies in the oral cavity.