Optimal dose and exercise modality to improve HbA1c in older adults with type 2 diabetes mellitus: a systematic review with pairwise, network, and dose-response meta-analyses.
Yumi Park, Young-Heon Shin, Yuan Yuan et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the effects of various exercise modalities on HbA1c levels in older adults with type 2 diabetes mellitus. The study found that high-intensity interval training (HIIT) resulted in the largest reduction in HbA1c (MD = -0.95%; 95% CrI -1.45, -0.49) compared to control, followed by combined exercise and continuous aerobic exercise. The analysis included randomized controlled trials and assessed dose-response relationships.
Key findings
- HIIT showed the largest HbA1c reduction of -0.95% compared to control.
- Combined exercise resulted in a reduction of -0.59% in HbA1c.
- Continuous aerobic exercise led to a -0.46% decrease in HbA1c levels.
- Maximal benefits in HbA1c reduction were observed at approximately 704 METs-min/week.
Why it matters
Understanding the impact of different exercise modalities on glycemic control is crucial for optimizing management strategies in older adults with type 2 diabetes. Tailoring exercise prescriptions can enhance patient outcomes and improve overall health.