Failure modes and effects analysis for clinical implementation of online adaptive radiotherapy: A systematic review.

J Appl Clin Med PhysSep 1, 2026
Clinical ResearchRadiology (Diagnostic)Open access

Deepikaa Balaji, Sonja Wegener, Sebastian Klüter et al.

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In 30 seconds

This systematic review examined the application of Failure Modes and Effects Analysis (FMEA) in Online Adaptive Radiotherapy (OART) across various systems. Eleven studies were analyzed, revealing 300 unique failure modes, with 49.6% classified as high-risk. The majority of these high-risk failures occurred during online treatment delivery, particularly in human-computer interactions and anatomical contouring.

Key findings

  • 300 unique failure modes were identified in OART workflows.
  • 49.6% of failure modes were classified as high-risk (Class III).
  • High-risk failures predominantly occurred during online treatment delivery.
  • Key areas of concern included human-computer interactions and anatomical contouring.

Why it matters

Understanding the failure modes in OART is crucial for enhancing patient safety and treatment efficacy. By identifying high-risk areas, clinicians can develop targeted quality assurance protocols to mitigate risks associated with adaptive radiotherapy.

Source

Published in J Appl Clin Med Phys. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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