Tranilast/roxithromycin with topical tacrolimus in refractory atopic facial eczema: Case report.

Int J Clin Pharmacol TherOct 16, 2026
Case ReportDermatology

Yasuhiro Horiuchi

✦ AI-curated · Sources linked

Case in brief

A 30-year-old man with atopic dermatitis had facial eczema and severe itching that persisted despite conventional treatment, including oral betamethasone. He received topical pediatric 0.03% tacrolimus ointment alongside tranilast 200 mg/day and roxithromycin 300 mg/day. Within 3 weeks, the facial eczema and itching had completely resolved.

What made this case unusual

The refractory facial eczema resolved after a regimen combining topical tacrolimus with oral tranilast and roxithromycin.

Diagnostic / clinical pearl

In this case, persistent facial eczema associated with atopic dermatitis resolved with topical tacrolimus plus oral tranilast and roxithromycin.

Source

PubMed · PMID 42638546

Published in Int J Clin Pharmacol Ther. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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