Exploring the dose-response relationship between prenatal exercise and postpartum depression: A systematic review and meta-analysis of randomized controlled trials.
Zhuoling Lei, Pengwei Ma, Zhuolin Xue et al.
✦ AI-curated · Sources linked
In 30 seconds
This systematic review and meta-analysis of randomized controlled trials examined the relationship between prenatal exercise and postpartum depression (PPD) in 2231 pregnant women. The analysis indicated that while prenatal exercise may reduce PPD incidence, the overall effect was not statistically significant (OR=0.58, 95% CI [0.33, 1.02]). However, exercise doses of ≥500 METs-min/week were associated with a significant reduction in PPD (OR=0.44, 95% CI [0.24, 0.78]).
Key findings
- Prenatal exercise was associated with a potential reduction in PPD incidence (OR=0.58, 95% CI [0.33, 1.02]).
- Exercise doses of ≥500 METs-min/week significantly reduced PPD incidence (OR=0.44, 95% CI [0.24, 0.78]).
- Subgroup analyses suggested trends toward greater benefits for women aged ≥30 years.
- The linear dose-response trend did not reach statistical significance (p = 0.0533).
Why it matters
Understanding the impact of prenatal exercise on postpartum depression is crucial for developing nonpharmacological prevention strategies. This research highlights the potential benefits of exercise during pregnancy, which could inform clinical recommendations and support maternal mental health.